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Platelet Surface-Associated Activation and Secretion-Mediated Inhibition of Coagulation Factor XII
Coagulation factor XII (fXII) is important for arterial thrombosis, but its physiological activation mechanisms are unclear. In this study, we elucidated the role of platelets and platelet-derived material in fXII activation. FXII activation was only observed upon potent platelet stimulation (with t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331558/ https://www.ncbi.nlm.nih.gov/pubmed/25688860 http://dx.doi.org/10.1371/journal.pone.0116665 |