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Early etiology of Alzheimer’s disease: tipping the balance toward autophagy or endosomal dysfunction?
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. This brain neuropathology is characterized by a progressive synaptic dysfunction and neuronal loss, which lead to decline in memory and other cognitive functions. Histopathologically, AD manifests via synaptic abnormalities...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331606/ https://www.ncbi.nlm.nih.gov/pubmed/25556159 http://dx.doi.org/10.1007/s00401-014-1379-7 |