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Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen

The effects of hypoxia on gene expression have been vigorously studied, but possible effects of small changes in oxygen tension have never been addressed. SUR2A is an atypical ABC protein serving as a regulatory subunit of sarcolemmal ATP-sensitive K(+) (K(ATP)) channels. Up-regulation of SUR2A is a...

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Detalles Bibliográficos
Autores principales: Mohammed Abdul, Khaja Shameem, Jovanović, Sofija, Sukhodub, Andriy, Du, Qingyou, Jovanović, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331663/
https://www.ncbi.nlm.nih.gov/pubmed/25064694
http://dx.doi.org/10.1016/j.bbamcr.2014.07.007