Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals

Pdr16p is considered a factor of clinical azole resistance in fungal pathogens. The most distinct phenotype of yeast cells lacking Pdr16p is their increased susceptibility to azole and morpholine antifungals. Pdr16p (also known as Sfh3p) of Saccharomyces cerevisiae belongs to the Sec14 family of pho...

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Detalles Bibliográficos
Autores principales: Holič, Roman, Šimová, Zuzana, Ashlin, Tim, Pevala, Vladimír, Poloncová, Katarína, Tahotná, Dana, Kutejová, Eva, Cockcroft, Shamshad, Griač, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331669/
https://www.ncbi.nlm.nih.gov/pubmed/25066473
http://dx.doi.org/10.1016/j.bbalip.2014.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331669/
https://www.ncbi.nlm.nih.gov/pubmed/25066473
http://dx.doi.org/10.1016/j.bbalip.2014.07.014

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