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MixClone: a mixture model for inferring tumor subclonal populations
BACKGROUND: Tumor genomes are often highly heterogeneous, consisting of genomes from multiple subclonal types. Complete characterization of all subclonal types is a fundamental need in tumor genome analysis. With the advancement of next-generation sequencing, computational methods have recently been...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331709/ https://www.ncbi.nlm.nih.gov/pubmed/25707430 http://dx.doi.org/10.1186/1471-2164-16-S2-S1 |