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MixClone: a mixture model for inferring tumor subclonal populations

BACKGROUND: Tumor genomes are often highly heterogeneous, consisting of genomes from multiple subclonal types. Complete characterization of all subclonal types is a fundamental need in tumor genome analysis. With the advancement of next-generation sequencing, computational methods have recently been...

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Detalles Bibliográficos
Autores principales: Li, Yi, Xie, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331709/
https://www.ncbi.nlm.nih.gov/pubmed/25707430
http://dx.doi.org/10.1186/1471-2164-16-S2-S1