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HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data

BACKGROUND: Human leucocyte antigen (HLA) genes play an important role in determining the outcome of organ transplantation and are linked to many human diseases. Because of the diversity and polymorphisms of HLA loci, HLA typing at high resolution is challenging even with whole-genome sequencing dat...

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Detalles Bibliográficos
Autores principales: Nariai, Naoki, Kojima, Kaname, Saito, Sakae, Mimori, Takahiro, Sato, Yukuto, Kawai, Yosuke, Yamaguchi-Kabata, Yumi, Yasuda, Jun, Nagasaki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331721/
https://www.ncbi.nlm.nih.gov/pubmed/25708870
http://dx.doi.org/10.1186/1471-2164-16-S2-S7