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HLA-VBSeq: accurate HLA typing at full resolution from whole-genome sequencing data
BACKGROUND: Human leucocyte antigen (HLA) genes play an important role in determining the outcome of organ transplantation and are linked to many human diseases. Because of the diversity and polymorphisms of HLA loci, HLA typing at high resolution is challenging even with whole-genome sequencing dat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331721/ https://www.ncbi.nlm.nih.gov/pubmed/25708870 http://dx.doi.org/10.1186/1471-2164-16-S2-S7 |