Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance

To determine whether Bmi-1 deficiency could lead to renal tubulointerstitial injury by mitochondrial dysfunction and increased oxidative stress in the kidney, 3-week-old Bmi-1(-/-) mice were treated with the antioxidant N-acetylcysteine (NAC, 1 mg mL(−1)) in their drinking water, or pyrro-quinoline...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Jianliang, Lv, Xianhui, Chen, Lulu, Zhang, Wei, Li, Jinbo, Wang, Qian, Wang, Rong, Lu, Xiang, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331754/
https://www.ncbi.nlm.nih.gov/pubmed/24915841
http://dx.doi.org/10.1111/acel.12236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331754/
https://www.ncbi.nlm.nih.gov/pubmed/24915841
http://dx.doi.org/10.1111/acel.12236

Ejemplares similares