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Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance

To determine whether Bmi-1 deficiency could lead to renal tubulointerstitial injury by mitochondrial dysfunction and increased oxidative stress in the kidney, 3-week-old Bmi-1(-/-) mice were treated with the antioxidant N-acetylcysteine (NAC, 1 mg mL(−1)) in their drinking water, or pyrro-quinoline...

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Detalles Bibliográficos
Autores principales:	Jin, Jianliang, Lv, Xianhui, Chen, Lulu, Zhang, Wei, Li, Jinbo, Wang, Qian, Wang, Rong, Lu, Xiang, Miao, Dengshun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331754/ https://www.ncbi.nlm.nih.gov/pubmed/24915841 http://dx.doi.org/10.1111/acel.12236

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