MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts

Age-related defects in fibroblast differentiation were previously shown to be associated with impaired hyaluronan synthase 2 (HAS2) and epidermal growth factor receptor (EGFR) function, with both required for normal fibroblast functionality. In fibroblasts, transforming growth factor-beta 1 (TGF-β1)...

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Detalles Bibliográficos
Autores principales: Midgley, Adam C, Bowen, Timothy, Phillips, Aled O, Steadman, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331777/
https://www.ncbi.nlm.nih.gov/pubmed/24134702
http://dx.doi.org/10.1111/acel.12167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331777/
https://www.ncbi.nlm.nih.gov/pubmed/24134702
http://dx.doi.org/10.1111/acel.12167

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