Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development

Hutchinson–Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) are two laminopathies caused by mutations leading to cellular accumulation of prelamin A or one of its truncated forms, progerin. One proposed mechanism for the more severe symptoms in patients with RD compared with HGPS is...

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Detalles Bibliográficos
Autores principales: McKenna, Tomás, Rosengardten, Ylva, Viceconte, Nikenza, Baek, Jean-Ha, Grochová, Diana, Eriksson, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331787/
https://www.ncbi.nlm.nih.gov/pubmed/24305605
http://dx.doi.org/10.1111/acel.12173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331787/
https://www.ncbi.nlm.nih.gov/pubmed/24305605
http://dx.doi.org/10.1111/acel.12173

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