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Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein–protein interaction modules as robust markers of human aging

The bodily decline that occurs with advancing age strongly impacts on the prospects for future health and life expectancy. Despite the profound role of age in disease etiology, knowledge about the molecular mechanisms driving the process of aging in humans is limited. Here, we used an integrative ne...

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Detalles Bibliográficos
Autores principales: van den Akker, Erik B, Passtoors, Willemijn M, Jansen, Rick, van Zwet, Erik W, Goeman, Jelle J, Hulsman, Marc, Emilsson, Valur, Perola, Markus, Willemsen, Gonneke, Penninx, Brenda WJH, Heijmans, Bas T, Maier, Andrea B, Boomsma, Dorret I, Kok, Joost N, Slagboom, Pieternella E, Reinders, Marcel JT, Beekman, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331790/
https://www.ncbi.nlm.nih.gov/pubmed/24119000
http://dx.doi.org/10.1111/acel.12160