Cargando…

Zinc Mediated Azide–Alkyne Ligation to 1,5- and 1,4,5-Substituted 1,2,3-Triazoles

[Image: see text] A mild method for regioselective formation of 1,5-substituted 1,2,3-triazoles is described. The zinc-mediated reaction works at room temperature and is successful across a wide range of azido/alkynyl substrates. Additionally, the triazole 4-position can be further functionalized th...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Christopher D., Greaney, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331842/
https://www.ncbi.nlm.nih.gov/pubmed/24001177
http://dx.doi.org/10.1021/ol402225d