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Evaluating Methods for Modeling Epistasis Networks with Application to Head and Neck Cancer

Epistasis helps to explain how multiple single-nucleotide polymorphisms (SNPs) interact to cause disease. A variety of tools have been developed to detect epistasis. In this article, we explore the strengths and weaknesses of an information theory approach for detecting epistasis and compare it to t...

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Detalles Bibliográficos
Autores principales: Talluri, Rajesh, Shete, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332043/
https://www.ncbi.nlm.nih.gov/pubmed/25733798
http://dx.doi.org/10.4137/CIN.S17289