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Evaluating Methods for Modeling Epistasis Networks with Application to Head and Neck Cancer
Epistasis helps to explain how multiple single-nucleotide polymorphisms (SNPs) interact to cause disease. A variety of tools have been developed to detect epistasis. In this article, we explore the strengths and weaknesses of an information theory approach for detecting epistasis and compare it to t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332043/ https://www.ncbi.nlm.nih.gov/pubmed/25733798 http://dx.doi.org/10.4137/CIN.S17289 |