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Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness
The concept of robustness in biology has gained much attention recently, but a mechanistic understanding of how genetic networks regulate phenotypic variation has remained elusive. One approach to understand the genetic architecture of variability has been to analyze dispensable gene deletions in mo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332149/ https://www.ncbi.nlm.nih.gov/pubmed/25609648 http://dx.doi.org/10.15252/msb.20145264 |