Reversal of glucose intolerance in rat offspring exposed to ethanol before birth through reduction of nuclear skeletal muscle HDAC expression by the bile acid TUDCA

Prenatal ethanol exposure causes cellular stress, insulin resistance, and glucose intolerance in adult offspring, with increased gluconeogenesis and reduced muscle glucose transporter‐4 (glut4) expression. Impaired insulin activation of Akt and nuclear translocation of histone deacetylases (HDACs) i...

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Detalles Bibliográficos
Autores principales: Yao, Xing‐Hai, Nguyen, Khanh H., Nyomba, B. L. Grégoire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332199/
https://www.ncbi.nlm.nih.gov/pubmed/25538147
http://dx.doi.org/10.14814/phy2.12195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332199/
https://www.ncbi.nlm.nih.gov/pubmed/25538147
http://dx.doi.org/10.14814/phy2.12195

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