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Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease

Heterocyclic dithiocarbamates have anti‐inflammatory and anti‐proliferative effects in rodent models of chronic kidney disease. In this study, we tested the hypothesis that pyrrolidine dithiocarbamate (PDTC) reduces the progression of polycystic kidney disease (PKD). Male Lewis polycystic kidney (LP...

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Detalles Bibliográficos
Autores principales: Ta, Michelle H. T., Rao, Padmashree, Korgaonkar, Mayuresh, Foster, Sheryl F., Peduto, Anthony, Harris, David C. H., Rangan, Gopala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332200/
https://www.ncbi.nlm.nih.gov/pubmed/25501440
http://dx.doi.org/10.14814/phy2.12196