Cargando…

Pyrrolidine dithiocarbamate reduces the progression of total kidney volume and cyst enlargement in experimental polycystic kidney disease

Heterocyclic dithiocarbamates have anti‐inflammatory and anti‐proliferative effects in rodent models of chronic kidney disease. In this study, we tested the hypothesis that pyrrolidine dithiocarbamate (PDTC) reduces the progression of polycystic kidney disease (PKD). Male Lewis polycystic kidney (LP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ta, Michelle H. T., Rao, Padmashree, Korgaonkar, Mayuresh, Foster, Sheryl F., Peduto, Anthony, Harris, David C. H., Rangan, Gopala K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Periodicals, Inc. 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332200/ https://www.ncbi.nlm.nih.gov/pubmed/25501440 http://dx.doi.org/10.14814/phy2.12196

Ejemplares similares

Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells
por: Ta, Michelle H. T., et al.
Publicado: (2015)

Effects of TORC1 Inhibition during the Early and Established Phases of Polycystic Kidney Disease
por: Ta, Michelle H. T., et al.
Publicado: (2016)

Kidney Cyst Lining Epithelial Cells Are Resistant to Low-Dose Cisplatin-Induced DNA Damage in a Preclinical Model of Autosomal Dominant Polycystic Kidney Disease
por: Saravanabavan, Sayanthooran, et al.
Publicado: (2022)

Role of DNA-Dependent Protein Kinase in Mediating Cyst Growth in Autosomal Dominant Polycystic Kidney Disease
por: Chandra, Ashley N., et al.
Publicado: (2021)

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes
por: Liddell, Jeffrey R., et al.
Publicado: (2016)

Regression of Peritubular Capillaries Coincides with Angiogenesis and Renal Cyst Growth in Experimental Polycystic Kidney Disease
por: O’Brien, Kristal, et al.
Publicado: (2020)

Pyrrolidine Dithiocarbamate Attenuates Paraquat-Induced Lung Injury in Rats
por: Chang, Xiuli, et al.
Publicado: (2009)

Therapeutic effects of pyrrolidine dithiocarbamate on acute lung injury in rabbits
por: Wang, Meitang, et al.
Publicado: (2011)

Pyrrolidine Dithiocarbamate Suppresses Cutibacterium acnes-Induced Skin Inflammation
por: Shin, Jin Hak, et al.
Publicado: (2023)

Pyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats
por: Kan, Min Hui, et al.
Publicado: (2016)

Is serum copeptin a modifiable biomarker in autosomal dominant polycystic kidney disease?
por: Tasneem, Moomal, et al.
Publicado: (2018)

Incidence and survival of end-stage kidney disease due to polycystic kidney disease in Australia and New Zealand (1963–2014)
por: Fernando, Mangalee R., et al.
Publicado: (2017)

Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells
por: JAKUBOWSKA-MUĆKA, ANNA, et al.
Publicado: (2012)

Bidirectional Effects of Pyrrolidine Dithiocarbamate on Severe Acute Pancreatitis in a Rat Model
por: Yang, Huan, et al.
Publicado: (2019)

Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease
por: Zhang, Jennifer Q. J., et al.
Publicado: (2021)

Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis
por: Miao, Chunxiao, et al.
Publicado: (2017)

Pyrrolidine Dithiocarbamate Might Mitigate Radiation-Induced Heart Damage at an Early Stage in Rats
por: Wu, Yajing, et al.
Publicado: (2022)

Participant Perceptions in a Long-term Clinical Trial of Autosomal Dominant Polycystic Kidney Disease
por: Amin, Sneha, et al.
Publicado: (2023)

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD)
por: Wong, Annette T Y, et al.
Publicado: (2018)

Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease
por: Sagar, Priyanka S., et al.
Publicado: (2021)

Relative Validity of a Beverage Frequency Questionnaire Used to Assess Fluid Intake in the Autosomal Dominant Polycystic Kidney Disease Population
por: Mannix, Carly, et al.
Publicado: (2018)

Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease
por: Zhang, Jennifer Q. J., et al.
Publicado: (2021)

Pyrrolidine Dithiocarbamate Attenuates Cardiocyte Apoptosis and Ameliorates Heart Failure Following Coronary Microembolization in Rats
por: Li, Shumei, et al.
Publicado: (2019)

Autosomal dominant polycystic kidney disease (ADPKD) is associated with coronary arterial dilatation in end-stage renal failure patients
por: Chiha, Joseph, et al.
Publicado: (2012)

Role of extracellular ATP and P2 receptor signaling in regulating renal cyst growth and interstitial inflammation in polycystic kidney disease
por: Rangan, Gopi
Publicado: (2013)

Cinacalcet may suppress kidney enlargement in hemodialysis patients with autosomal dominant polycystic kidney disease
por: Nakatani, Shinya, et al.
Publicado: (2021)

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity
por: Lu, Chang-Wu, et al.
Publicado: (2017)

Pyrrolidine Dithiocarbamate Facilitates Arsenic Trioxide Against Pancreatic Cancer via Perturbing Ubiquitin-Proteasome Pathway
por: Yu, Simin, et al.
Publicado: (2020)

Adipogenic Stimulation and Pyrrolidine Dithiocarbamate Induced Osteogenic Inhibition of Dental Pulp Stem Cells Is Countered by Cordycepin
por: Patil, Shankargouda, et al.
Publicado: (2021)

Increased water intake reduces long-term renal and cardiovascular disease progression in experimental polycystic kidney disease
por: Sagar, Priyanka S., et al.
Publicado: (2019)

Kidney volume and function in autosomal dominant polycystic kidney disease
por: Higashihara, Eiji, et al.
Publicado: (2013)

Drug management of autosomal dominant polycystic kidney disease
por: Theivendran, Thiveya, et al.
Publicado: (2022)

Cyst infection in hospital-admitted autosomal dominant polycystic kidney disease patients is predominantly multifocal and associated with kidney and liver volume
por: Balbo, B.E.P., et al.
Publicado: (2014)

Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
por: Daniel, Kenyon G, et al.
Publicado: (2005)

Regulatory mechanism of pyrrolidine dithiocarbamate is mediated by nuclear factor-κB and inhibits neutrophil accumulation in ARDS mice
por: WANG, HONGMAN, et al.
Publicado: (2014)

Protective Effects of the Nuclear Factor Kappa B Inhibitor Pyrrolidine Dithiocarbamate on Experimental Testicular Torsion and Detorsion Injury
por: Kabay, Sahin, et al.
Publicado: (2014)

Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL
por: Tang, Jun-Hai, et al.
Publicado: (2017)

Short-term pyrrolidine dithiocarbamate administration attenuates cachexia-induced alterations to muscle and liver in Apc(Min/+) mice
por: Narsale, Aditi A., et al.
Publicado: (2016)

Inhibition of nuclear factor-κB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury
por: Yang, Hongfu, et al.
Publicado: (2017)

Multiple Cysts in the Kidney and Lungs in a Patient with Polycystic Kidney Disease and Lymphangioleiomyomatosis
por: Lam, Anna P., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_b6kcsllo7abmefvh3lo8q27fjj