Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans

Hypoxia causes an increase in pulmonary artery pressure. Gene expression controlled by the hypoxia‐inducible factor (HIF) family of transcription factors plays an important role in the underlying pulmonary vascular responses. The hydroxylase enzymes that regulate HIF are highly sensitive to varying...

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Detalles Bibliográficos
Autores principales: Talbot, Nick P., Croft, Quentin P., Curtis, M. Kate, Turner, Brandon E., Dorrington, Keith L., Robbins, Peter A., Smith, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332205/
https://www.ncbi.nlm.nih.gov/pubmed/25501423
http://dx.doi.org/10.14814/phy2.12220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332205/
https://www.ncbi.nlm.nih.gov/pubmed/25501423
http://dx.doi.org/10.14814/phy2.12220

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