Altering the redox state of skeletal muscle by glutathione depletion increases the exercise‐activation of PGC‐1α

We investigated the relationship between markers of mitochondrial biogenesis, cell signaling, and antioxidant enzymes by depleting skeletal muscle glutathione with diethyl maleate (DEM) which resulted in a demonstrable increase in oxidative stress during exercise. Animals were divided into six group...

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Detalles Bibliográficos
Autores principales: Strobel, Natalie A., Matsumoto, Aya, Peake, Jonathan M., Marsh, Susan A., Peternelj, Tina‐Tinkara, Briskey, David, Fassett, Robert G., Coombes, Jeff S., Wadley, Glenn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332207/
https://www.ncbi.nlm.nih.gov/pubmed/25538148
http://dx.doi.org/10.14814/phy2.12224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332207/
https://www.ncbi.nlm.nih.gov/pubmed/25538148
http://dx.doi.org/10.14814/phy2.12224

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