Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K‐ATPase, FXYD2

Na,K‐ATPase generates the driving force for sodium reabsorption in the kidney. Na,K‐ATPase functional properties are regulated by small proteins belonging to the FXYD family. In kidney FXYD2 is the most abundant: it is an inhibitory subunit expressed in almost every nephron segment. Its absence shou...

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Detalles Bibliográficos
Autores principales: Arystarkhova, Elena, Ralph, Donna L., Liu, Yi Bessie, Bouley, Richard, McDonough, Alicia A., Sweadner, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332208/
https://www.ncbi.nlm.nih.gov/pubmed/25472608
http://dx.doi.org/10.14814/phy2.12226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332208/
https://www.ncbi.nlm.nih.gov/pubmed/25472608
http://dx.doi.org/10.14814/phy2.12226

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