Insulin resistance and muscle insulin receptor substrate‐1 serine hyperphosphorylation

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin‐responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate‐1 (IRS‐1) at Tyr896 is a necessary step...

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Detalles Bibliográficos
Autores principales: Stuart, Charles A., Howell, Mary E. A., Cartwright, Brian M., McCurry, Melanie P., Lee, Michelle L., Ramsey, Michael W., Stone, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://www.ncbi.nlm.nih.gov/pubmed/25472611
http://dx.doi.org/10.14814/phy2.12236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332214/
https://www.ncbi.nlm.nih.gov/pubmed/25472611
http://dx.doi.org/10.14814/phy2.12236

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