The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility

Integrity of the dendritic cell (DC) actin cytoskeleton is essential for T cell priming, but the underlying mechanisms are poorly understood. We show that the DC F-actin network regulates the lateral mobility of intracellular cell adhesion molecule 1 (ICAM-1), but not MHCII. ICAM-1 mobility and clus...

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Detalles Bibliográficos
Autores principales: Comrie, William A., Li, Shuixing, Boyle, Sarah, Burkhardt, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332244/
https://www.ncbi.nlm.nih.gov/pubmed/25666808
http://dx.doi.org/10.1083/jcb.201406120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332244/
https://www.ncbi.nlm.nih.gov/pubmed/25666808
http://dx.doi.org/10.1083/jcb.201406120

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