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Legal but lethal: functional protein aggregation at the verge of toxicity

Many neurodegenerative disorders are linked to irreversible protein aggregation, a process that usually comes along with toxicity and serious cellular damage. However, it is emerging that protein aggregation can also serve for physiological purposes, as impressively shown for prions. While the aggre...

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Detalles Bibliográficos
Autores principales: Falsone, Angelika, Falsone, S. Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332346/
https://www.ncbi.nlm.nih.gov/pubmed/25741240
http://dx.doi.org/10.3389/fncel.2015.00045