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Use of pharmacogenomics in pediatric renal transplant recipients

Transplant recipients receive potent immunosuppressive drugs in order to prevent graft rejection. Therapeutic drug monitoring is the current approach to guide the dosing of calcineurin inhibitors, mammalian target of rapamycin inhibitors (mTORi) and mofetil mycophenolate. Target concentrations used...

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Detalles Bibliográficos
Autores principales: Medeiros, Mara, Castañeda-Hernández, Gilberto, Ross, Colin J. D., Carleton, Bruce C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332348/
https://www.ncbi.nlm.nih.gov/pubmed/25741362
http://dx.doi.org/10.3389/fgene.2015.00041