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Malaria and the liver: immunological hide-and-seek or subversion of immunity from within?

During the pre-erythrocytic asymptomatic phase of malarial infection, sporozoites develop transiently inside less than 100 hepatocytes that subsequently release thousands of merozoites. Killing of these hepatocytes by cytotoxic T cells (CTLs) confers protection to subsequent malarial infection, sugg...

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Detalles Bibliográficos
Autores principales: Bertolino, Patrick, Bowen, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332352/
https://www.ncbi.nlm.nih.gov/pubmed/25741320
http://dx.doi.org/10.3389/fmicb.2015.00041