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Malaria and the liver: immunological hide-and-seek or subversion of immunity from within?
During the pre-erythrocytic asymptomatic phase of malarial infection, sporozoites develop transiently inside less than 100 hepatocytes that subsequently release thousands of merozoites. Killing of these hepatocytes by cytotoxic T cells (CTLs) confers protection to subsequent malarial infection, sugg...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332352/ https://www.ncbi.nlm.nih.gov/pubmed/25741320 http://dx.doi.org/10.3389/fmicb.2015.00041 |