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Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges

Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder characterized by a multi-systemic vascular dysplasia and hemorrhage. The precise factors leading to these vascular malformations are not yet understood and robust animal models of HHT are essential to gain a detailed understanding of...

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Detalles Bibliográficos
Autores principales: Tual-Chalot, Simon, Oh, S. Paul, Arthur, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332371/
https://www.ncbi.nlm.nih.gov/pubmed/25741358
http://dx.doi.org/10.3389/fgene.2015.00025