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Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings

Chemical denaturant titrations can be used to accurately determine protein stability. However, data acquisition is typically labour intensive, has low throughput and is difficult to automate. These factors, combined with high protein consumption, have limited the adoption of chemical denaturant titr...

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Detalles Bibliográficos
Autores principales: Alexander, Crispin G., Wanner, Randy, Johnson, Christopher M., Breitsprecher, Dennis, Winter, Gerhard, Duhr, Stefan, Baaske, Philipp, Ferguson, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332417/
https://www.ncbi.nlm.nih.gov/pubmed/25262836
http://dx.doi.org/10.1016/j.bbapap.2014.09.016