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Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings
Chemical denaturant titrations can be used to accurately determine protein stability. However, data acquisition is typically labour intensive, has low throughput and is difficult to automate. These factors, combined with high protein consumption, have limited the adoption of chemical denaturant titr...
Autores principales: | Alexander, Crispin G., Wanner, Randy, Johnson, Christopher M., Breitsprecher, Dennis, Winter, Gerhard, Duhr, Stefan, Baaske, Philipp, Ferguson, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332417/ https://www.ncbi.nlm.nih.gov/pubmed/25262836 http://dx.doi.org/10.1016/j.bbapap.2014.09.016 |
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