Deletion of AU-Rich Elements within the Bcl2 3′UTR Reduces Protein Expression and B Cell Survival In Vivo

Post-transcriptional mRNA regulation by RNA binding proteins (RBPs) associated with AU-rich elements (AREs) present in the 3′ untranslated region (3’UTR) of specific mRNAs modulates transcript stability and translation in eukaryotic cells. Here we have functionally characterised the importance of th...

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Detalles Bibliográficos
Autores principales: Díaz-Muñoz, Manuel D., Bell, Sarah E., Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332480/
https://www.ncbi.nlm.nih.gov/pubmed/25680182
http://dx.doi.org/10.1371/journal.pone.0116899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332480/
https://www.ncbi.nlm.nih.gov/pubmed/25680182
http://dx.doi.org/10.1371/journal.pone.0116899

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