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Solution NMR studies reveal the location of the second transmembrane domain of the human sigma-1 receptor

The sigma-1 receptor (S1R) is a ligand-regulated membrane chaperone protein associated with endoplasmic reticulum stress response, and modulation of ion channel activities at the plasma membrane. We report here a solution NMR study of a S1R construct (S1R(Δ35)) in which only the first transmembrane...

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Detalles Bibliográficos
Autores principales: Ortega-Roldan, Jose Luis, Ossa, Felipe, Amin, Nader T., Schnell, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332692/
https://www.ncbi.nlm.nih.gov/pubmed/25647032
http://dx.doi.org/10.1016/j.febslet.2015.01.033