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Curing a viral infection by targeting the host: The example of cyclophilin inhibitors

Every step of the viral life cycle is dependent on the host, which potentially can be explored for antiviral targets. Historically, however, drug discovery has focused mainly on viral targets, because of their perceived specificity. Efforts to pursue host targets have been largely hampered by concer...

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Detalles Bibliográficos
Autores principales: Lin, Kai, Gallay, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332838/
https://www.ncbi.nlm.nih.gov/pubmed/23578729
http://dx.doi.org/10.1016/j.antiviral.2013.03.020