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Hexon Modification to Improve the Activity of Oncolytic Adenovirus Vectors against Neoplastic and Stromal Cells in Pancreatic Cancer

Primary pancreatic carcinoma has an unfavourable prognosis and standard treatment strategies mostly fail in advanced cases. Virotherapy might overcome this resistance to current treatment modalities. However, data from clinical studies with oncolytic viruses, including replicating adenoviral (Ad) ve...

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Detalles Bibliográficos
Autores principales: Lucas, Tanja, Benihoud, Karim, Vigant, Frédéric, Schmidt, Christoph Q. Andreas, Bachem, Max G., Simmet, Thomas, Kochanek, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332860/
https://www.ncbi.nlm.nih.gov/pubmed/25692292
http://dx.doi.org/10.1371/journal.pone.0117254