MMP-12-mediated by SARM-TRIF signaling pathway contributes to IFN-γ-independent airway inflammation and AHR post RSV infection in nude mice

BACKGROUND: Respiratory syncytial virus (RSV) is one of the most frequently observed pathogens during infancy and childhood. However, the corresponding pathogenesis has not been determined to date. We previously demonstrated that IFN-γ plays an important role in RSV pathogenesis, and SARM-TRIF-signa...

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Detalles Bibliográficos
Autores principales: Long, Xiaoru, Li, Simin, Xie, Jun, Li, Wei, Zang, Na, Ren, Luo, Deng, Yu, Xie, Xiaohong, Wang, Lijia, Fu, Zhou, Liu, Enmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332892/
https://www.ncbi.nlm.nih.gov/pubmed/25652021
http://dx.doi.org/10.1186/s12931-015-0176-8