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Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2
BACKGROUND: The nuclear receptor liver X receptor (LXR) exerts transcriptional control over lipid metabolism and inflammatory response in cells of the myeloid lineage, suggesting that LXR may be a potential target in a number of chronic neuroinflammatory and neurodegenerative diseases where persiste...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332930/ https://www.ncbi.nlm.nih.gov/pubmed/25889344 http://dx.doi.org/10.1186/s12974-015-0247-2 |