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Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2

BACKGROUND: The nuclear receptor liver X receptor (LXR) exerts transcriptional control over lipid metabolism and inflammatory response in cells of the myeloid lineage, suggesting that LXR may be a potential target in a number of chronic neuroinflammatory and neurodegenerative diseases where persiste...

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Detalles Bibliográficos
Autores principales: Secor McVoy, Julie R, Oughli, Hanadi Ajam, Oh, Unsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332930/
https://www.ncbi.nlm.nih.gov/pubmed/25889344
http://dx.doi.org/10.1186/s12974-015-0247-2