Cargando…

Modular construction of mammalian gene circuits using TALE transcriptional repressors

An important goal of synthetic biology is the rational design and predictable implementation of synthetic gene circuits using standardized and interchangeable parts. However, engineering of complex circuits in mammalian cells is currently limited by the availability of well-characterized and orthogo...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yinqing, Jiang, Yun, Chen, He, Liao, Weixi, Li, Zhihua, Weiss, Ron, Xie, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333066/
https://www.ncbi.nlm.nih.gov/pubmed/25643171
http://dx.doi.org/10.1038/nchembio.1736