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Modular construction of mammalian gene circuits using TALE transcriptional repressors
An important goal of synthetic biology is the rational design and predictable implementation of synthetic gene circuits using standardized and interchangeable parts. However, engineering of complex circuits in mammalian cells is currently limited by the availability of well-characterized and orthogo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333066/ https://www.ncbi.nlm.nih.gov/pubmed/25643171 http://dx.doi.org/10.1038/nchembio.1736 |