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Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children

BACKGROUND: Airway remodeling is a proposed mechanism that underlies the persistent loss of lung function associated with childhood asthma. Previous studies have demonstrated that human lung fibroblasts (HLFs) co-cultured with primary human bronchial epithelial cells (BECs) from asthmatic children e...

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Detalles Bibliográficos
Autores principales: Reeves, Stephen R, Kolstad, Tessa, Lien, Tin-Yu, Herrington-Shaner, Sarah, Debley, Jason S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333174/
https://www.ncbi.nlm.nih.gov/pubmed/25849331
http://dx.doi.org/10.1186/s12931-015-0185-7