A pharmacometric pulmonary model predicting the extent and rate of distribution from plasma to epithelial lining fluid and alveolar cells—using rifampicin as an example

PURPOSE: The purpose of the study was to develop a drug-unspecific approach to pharmacometric modeling for predicting the rate and extent of distribution from plasma to epithelial lining fluid (ELF) and alveolar cells (AC) for data emanating from studies involving bronchoalveolar lavage (BAL) sampli...

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Detalles Bibliográficos
Autores principales: Clewe, Oskar, Goutelle, Sylvain, Conte, John E., Simonsson, Ulrika S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333237/
https://www.ncbi.nlm.nih.gov/pubmed/25620089
http://dx.doi.org/10.1007/s00228-014-1798-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333237/
https://www.ncbi.nlm.nih.gov/pubmed/25620089
http://dx.doi.org/10.1007/s00228-014-1798-3

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