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Revealing the amino acid composition of proteins within an expanded genetic code

The genetic code can be manipulated to reassign codons for the incorporation of non-standard amino acids (NSAA). Deletion of release factor 1 in Escherichia coli enhances translation of UAG (Stop) codons, yet may also extended protein synthesis at natural UAG terminated messenger RNAs. The fidelity...

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Detalles Bibliográficos
Autores principales: Aerni, Hans R., Shifman, Mark A., Rogulina, Svetlana, O'Donoghue, Patrick, Rinehart, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333366/
https://www.ncbi.nlm.nih.gov/pubmed/25378305
http://dx.doi.org/10.1093/nar/gku1087