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Revealing the amino acid composition of proteins within an expanded genetic code
The genetic code can be manipulated to reassign codons for the incorporation of non-standard amino acids (NSAA). Deletion of release factor 1 in Escherichia coli enhances translation of UAG (Stop) codons, yet may also extended protein synthesis at natural UAG terminated messenger RNAs. The fidelity...
Autores principales: | Aerni, Hans R., Shifman, Mark A., Rogulina, Svetlana, O'Donoghue, Patrick, Rinehart, Jesse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333366/ https://www.ncbi.nlm.nih.gov/pubmed/25378305 http://dx.doi.org/10.1093/nar/gku1087 |
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