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Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions

Systematic interrogation of mutation or protein modification data is important to identify sites with functional consequences and to deduce global consequences from large data sets. Mechismo (mechismo.russellab.org) enables simultaneous consideration of thousands of 3D structures and biomolecular in...

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Detalles Bibliográficos
Autores principales: Betts, Matthew J., Lu, Qianhao, Jiang, YingYing, Drusko, Armin, Wichmann, Oliver, Utz, Mathias, Valtierra-Gutiérrez, Ilse A., Schlesner, Matthias, Jaeger, Natalie, Jones, David T., Pfister, Stefan, Lichter, Peter, Eils, Roland, Siebert, Reiner, Bork, Peer, Apic, Gordana, Gavin, Anne-Claude, Russell, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333368/
https://www.ncbi.nlm.nih.gov/pubmed/25392414
http://dx.doi.org/10.1093/nar/gku1094