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Exploiting post-transcriptional regulation to probe RNA structures in vivo via fluorescence
While RNA structures have been extensively characterized in vitro, very few techniques exist to probe RNA structures inside cells. Here, we have exploited mechanisms of post-transcriptional regulation to synthesize fluorescence-based probes that assay RNA structures in vivo. Our probing system invol...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333371/ https://www.ncbi.nlm.nih.gov/pubmed/25416800 http://dx.doi.org/10.1093/nar/gku1191 |