Exploiting post-transcriptional regulation to probe RNA structures in vivo via fluorescence

While RNA structures have been extensively characterized in vitro, very few techniques exist to probe RNA structures inside cells. Here, we have exploited mechanisms of post-transcriptional regulation to synthesize fluorescence-based probes that assay RNA structures in vivo. Our probing system invol...

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Detalles Bibliográficos
Autores principales: Sowa, Steven W., Vazquez-Anderson, Jorge, Clark, Chelsea A., De La Peña, Ricardo, Dunn, Kaitlin, Fung, Emily K., Khoury, Mark J., Contreras, Lydia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333371/
https://www.ncbi.nlm.nih.gov/pubmed/25416800
http://dx.doi.org/10.1093/nar/gku1191

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