Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome

The possibility that alterations in DNA methylation are mechanistic drivers of development, aging and susceptibility to disease is widely acknowledged, but evidence remains patchy or inconclusive. Of particular interest in this regard is the brain, where it has been reported that DNA methylation imp...

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Detalles Bibliográficos
Autores principales: Illingworth, Robert S., Gruenewald-Schneider, Ulrike, De Sousa, Dina, Webb, Shaun, Merusi, Cara, Kerr, Alastair R. W., James, Keith D., Smith, Colin, Walker, Robert, Andrews, Robert, Bird, Adrian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333374/
https://www.ncbi.nlm.nih.gov/pubmed/25572316
http://dx.doi.org/10.1093/nar/gku1305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333374/
https://www.ncbi.nlm.nih.gov/pubmed/25572316
http://dx.doi.org/10.1093/nar/gku1305

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