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Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome
The possibility that alterations in DNA methylation are mechanistic drivers of development, aging and susceptibility to disease is widely acknowledged, but evidence remains patchy or inconclusive. Of particular interest in this regard is the brain, where it has been reported that DNA methylation imp...
Autores principales: | Illingworth, Robert S., Gruenewald-Schneider, Ulrike, De Sousa, Dina, Webb, Shaun, Merusi, Cara, Kerr, Alastair R. W., James, Keith D., Smith, Colin, Walker, Robert, Andrews, Robert, Bird, Adrian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333374/ https://www.ncbi.nlm.nih.gov/pubmed/25572316 http://dx.doi.org/10.1093/nar/gku1305 |
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