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RNA structure generates natural cooperativity between single-stranded RNA binding proteins targeting 5′ and 3′UTRs
In post-transcriptional regulation, an mRNA molecule is bound by many proteins and/or miRNAs to modulate its function. To enable combinatorial gene regulation, these binding partners of an RNA must communicate with each other, exhibiting cooperativity. Even in the absence of direct physical interact...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333377/ https://www.ncbi.nlm.nih.gov/pubmed/25550422 http://dx.doi.org/10.1093/nar/gku1320 |