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RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway

Fanconi anemia (FA) patients exhibit bone marrow failure, developmental defects and cancer. The FA pathway maintains chromosomal stability in concert with replication fork maintenance and DNA double strand break (DSB) repair pathways including RAD51-mediated homologous recombination (HR). RAD51 is a...

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Detalles Bibliográficos
Autores principales: Kim, Tae Moon, Son, Mi Young, Dodds, Sherry, Hu, Lingchuan, Luo, Guangbin, Hasty, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333386/
https://www.ncbi.nlm.nih.gov/pubmed/25520194
http://dx.doi.org/10.1093/nar/gku1334