Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing

When messenger RNA splicing occurs co-transcriptionally, the potential for kinetic control based on transcription dynamics is widely recognized. Indeed, perturbation studies have reported that when transcription kinetics are perturbed genetically or pharmacologically splice patterns may change. Howe...

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Detalles Bibliográficos
Autores principales: Davis-Turak, Jeremy C., Allison, Karmel, Shokhirev, Maxim N., Ponomarenko, Petr, Tsimring, Lev S., Glass, Christopher K., Johnson, Tracy L., Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333389/
https://www.ncbi.nlm.nih.gov/pubmed/25541195
http://dx.doi.org/10.1093/nar/gku1338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333389/
https://www.ncbi.nlm.nih.gov/pubmed/25541195
http://dx.doi.org/10.1093/nar/gku1338

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